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TLR3在神经系统疾病中的研究进展

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摘要 Toll蛋白最早在果蝇体内被发现,约有8个同源体。随后研究发现Toll在昆虫的抗真菌天然免疫反应中发挥重要作用,1997年Janeway等研究首先发现与果蝇同源的人的Toll蛋白,并命名为Toll样受体（Toll-like receptors,TLRs）,至今已发现11种人的TLRs和13种小鼠TLRs。TLR家族在天然免疫中发挥着核心作用,
作者 王庆东 花放 崔桂云 陈伟 宋璞 王小鹏 沈霞
机构地区 徐州医学院附属医院神经内科
出处 《中国实用神经疾病杂志》 2012年第11期79-80,96,共3页 Chinese Journal of Practical Nervous Diseases
关键词 TLR3 DSRNA 神经系统疾病
分类号 R-332 [医药卫生]
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参考文献24

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二级参考文献44

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中国实用神经疾病杂志
2012年 第11期

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