12例视神经胶质瘤MRI分析

Analysis of MRI on 12 patients with optic nerve glioma

目的探讨视神经胶质瘤的MRI诊断及鉴别诊断。方法回顾分析12例经手术病理证实视神经胶质瘤的MRI表现及动态增强特征。结果不规则肿块5例,梭形增粗3例,纡曲形增粗4例。累及眶内段11例、管内段8例、球内段1例、视交叉4例、视束1例。肿瘤在T1WI上为略低、等信号,T2WI上为略高、等、低信号;信号均匀10例,肿瘤内有囊变而信号不均2例;肿瘤无强化3例,轻度强化6例,明显强化3例。9例行动态增强检查;时间信号曲线3例呈平直型,4例呈缓升型,2例呈速升平台型。结论 MRI在显示视神经胶质瘤位置形态、肿瘤侵犯范围、肿瘤信号特征均有典型表现。

Objective： To evaluate the diagnosis and the differential diagnosis by MRI on patient with optic nerve glioma. Materials and Methods： The manifestations of MRI were retrospectively analyzed in 12 patients with optic nerve glioma whom confirmed by the operation and pathology. Results： In the shape, it revealed as irregular in 5 cases, fusiibrmis 3 cases, tortuous 4 cases. The glioma involved the orbit in 11 cases, intracanal segment 8 cases, intraocular segment 1 case, optic chiasm 4 cases, optic tract 1 case. For MRL the presentations of the tumor revealed as iso- or hypointense signal oll T 1-weighted images, and iso- or hypointense, or hyperintense signal on T2-weighted images. In the tumor, there was homogeneous signal in 10 cases, and cyst lesions with inhomogenous signal in 2 cases, there was not enhanced in 3 cases, enhanced slightly 6 cases, enhanced obviously 3 cases. Nine patients were undergone dynamic contrast- enhanced MRI and time-signal intensity curve including flat in 3 cases, gentle slope in 4 cases and straight slope in 2 cases. Conclusion： It is typically to reveal the features of location, shape, and extent of optic nerve glioma on MRI. MRI is of great value to make a diagnosis and differential diagnosis on optic nerve glioma.