同卵孪生姐妹间肾移植一例报告

One case report: renal transplantation between the identical twin sister

目的 探讨同卵孪生姐妹间肾移植的手术方法及术后治疗。方法 术前对供者进行全面检查， 并检测ＨＬＡ 位点及ＳＴＲ 基因型。将孪生姐姐的右肾移植给孪生妹妹。移植肾静脉与受者的髂外静脉端侧吻合， 肾动脉与髂内动脉端端吻合。术后短期使用免疫抑制剂。结果 ＨＬＡ 及ＳＴＲ基因型的测定结果证明供、受者为同卵孪生姐妹； 供者取肾后无异常情况发生； 受者术后３ ｄ 血肌酐恢复正常； 术后使用免疫抑制剂（ 甲泼尼龙、环磷酰胺、泼尼松）１５ ｄ， 然后停用全部免疫抑制剂，随访观察７ 月余， 移植肾功能、肝功能完全正常， 无排斥反应发生。结论 同卵孪生姐妹间肾移植，术后不需长期使用免疫抑制剂， 移植后无排斥反应发生。

Objectives To investigate the operation technique and the post operative treatment in the renal transplantation between the identical twin sister.Methods The right kidney of the older sister was harvested and implanted into the younger sister. The renal artery was end to end anastomosed to the internal iliac artery and the renal vein end to side to the external iliac vein. The immunosuppressive agent was administrated during a short period after operation. Results The renal function restored to the normal level in 3 days. The immunosuppress agent was used for only 15 days. The renal function was normal and there was no rejection in the 7 months follow up. Conclusions The immunosuppressive agent needn't be used and no rejection occurs after renal transplantation between the identical twin sister.