感热宁颗粒治疗感冒的临床观察

Clinical Observation on Ganrening Granule in Treating Common Cold

目的 :观察感热宁颗粒用于感冒 (中医辨证属于卫气同病证 )的治疗。方法 :将 4 0 0例患者随机分为治疗组和对照组及开放组 ,治疗组共 16 0例 ,对照组 10 0例 ,开放组 140例 ,试验采用单盲法进行。治疗前、治疗中、治疗后观察体温、症状变化等 ,以《中药新药临床研究指导原则》作为疗效评定标准。结果 :治疗组 16 0例的总有效率为 96 88% ,愈显率为 81 2 5% ,对照组的总有效率为 88 0 0 % ,愈显率为 4 4 0 0 %(P <0 0 1) ,本药对感冒引起的发热有明显的退热效果。结论 :感热宁颗粒对感冒 (卫气同病证 )有明显的治疗作用 ,临床观察中未见明显的不良反应。

Objective: To explore the therapeutic effect of Ganrening Granule (GRN) in treating common cold. Methods: Four hundered cases of common cold were randomly divided into three groups, the GRN group (160 Patients), the control group (100 Patients) and the opened group (140 Patients). The changes in symptoms and body temperature of patients were observed before and after treatment by single blind method, and the therapeutic effect was assessed according to the “Guideline of Clinical Research of TCM New Drugs”. Results: The markedly effective rate and total effective rate of the GRN group were 81.25% and 96.88% respectively, while those of the control group were 44.44% and 88.00% respectively. The difference between the two groups was significant (P<0 01). GRN showed significant effect in subsiding fever. Conclusion: GRN has good effect in treating common cold (Syndrome of both Weifen and Qifen). No adverse effect was found in the clinical trial.