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醋酸甲地孕酮对肺癌患者生活质量的影响 被引量:1

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摘要 目的探讨醋酸甲地孕酮在肺癌化疗中的作用。方法将确诊为肺癌且具有化疗适应证的64例患者,随机分为治疗组和对照组。对照组34例行常规方案化疗,并行常规对症及支持治疗;治疗组30例在对照组治疗的基础上,于化疗当天开始每日口服醋酸甲地孕酮160 mg,连用1周观察患者的食欲、体质量及Karnofskp评分改变并记录不良反应。结果治疗组食欲增加22例,占73.3%;体质量增加18例,占58.9%;Karnofskp评分升高10分以上者16例,占53.3%。对照组食欲增加4例,占11.8%;体质量增加5例,占14.8%;Karnofskv评分升高10分以上者6例,占17.6%,两组比较差异有统计学意义(P<0.05)。结论醋酸甲地孕酮不仅能刺激患者的食欲、增加体质量,改善肺癌患者的生存质量,而且可以减轻化疗所致的胃肠道反应。还可明显减轻化疗的不良反应,提高化疗患者的生活质量,而且不良反应不明显。
出处 《临床医学》 CAS 2012年第3期61-62,共2页 Clinical Medicine
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