合并血脂增高酒精性胰腺炎患者临床观察

Clinical obseruation of alcoholic acute pancreatitis patients with hyperlipidemia

目的观察合并血脂增高酒精性胰腺炎患者病情及治疗后复发情况。方法选取自2010年1月至2011年4月在郯城县第一人民医院就诊的48例酒精性胰腺炎患者,根据血脂有无增高分为血脂增高组(Ⅰ组)和血脂正常组(Ⅱ组)。分别观察血清淀粉酶(AMY)、甘油三酯(TG)、总胆固醇(CHO)、丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、APACHEⅡ评分、CT严重指数、体质量指数,治疗后转归及复发情况。结果Ⅰ组与Ⅱ组比较,TG、CHO、ALT、AST、APACHEⅡ评分、CT严重指数、体质量指数显著增高,差异有统计学意义(P<0.05),AMY两组比较差异无统计学意义(P>0.05)。Ⅰ组与Ⅱ组比较,重症比例、6个月内复发率显著增高,差异有统计学意义(P<0.05)。结论合并高血脂酒精性胰腺炎患者病情较重,治疗后易复发。

Objective To observe the clinical characteristics of alcoholic acute pancreatitis patients with hyperlipidemia.Methods A total of 48 alcoholic acute pancreatitis patients were divided into two groups： hyperlipidemia group（Group Ⅰ） and ortholiposis group（Group Ⅱ）.AMY,TG,CHO,ALT,AST,APACHE Ⅱ,CT index,body mass index（BMI）,rehabilitation and recurrence were observed.Results TG,CHO,ALT,AST and APACHE Ⅱ,CT index,BMI were increased in group Ⅰ,compared with group Ⅱ（P〈0.05）.There was not significant difference in AMY between the two groups（P〈0.05）.The rates of recurrence within 6 months and severe case were higher in group Ⅰ than that in group Ⅱ（P〈0.05）.Conclusion Alcoholic acute pancreatitis with hyperlipidemia was more severe than ortholiposis patients,and with high recurrence rate.