糖耐量筛查阳性与妊娠糖尿病关系的探讨

Study in 50g glucose screening test with gestational diabetes mellitus

目的 进一步探讨糖筛查阳性与GDM的关系。方法 选择 1997年 3月～ 1998年 2月在我院门诊检查孕妇中 50g葡萄糖筛查阳性的 4 17例孕妇 ,全部通过OGTT试验 ,并分为三组 :正常组、OGTT异常组、GDM组 ,并就研究项目进行分组对照研究。结果 ①糖筛查阳性与OGTT异常检出密切相关 ;②伴随高危因素其糖筛查阳性的OGTT异常检出率明显增加 ;③糖筛查值≥ 10mmol/L时 ,其GDM发生率上升明显 ;④各个孕周筛查OGTT异常 ,检出无显著性差异 ,孕早期仍有 2 7 3%GDM被检出。结论 糖筛查对诊断GDM是十分必要的。尤其结果为阳性的孕妇 ,无论任何孕周都是有意义的 ,即便是孕早期发现糖筛查阳性 ,均应及时行OGTT检查 ,以便及时诊断。特别是伴有高危因素的孕妇 ,或糖筛查值≥ 10mmol/L的孕妇 ,应高度警惕GDM的发生 ,及时行OGTT ,及早发现 ,及早处理。

Objective To research in 50g glucose screening test (GST) with gestational diabetes mellitus (GDM).Methods Selecting 417 pregnant women who were tested positive of 50g GST in our clinic from March 1997 to February 1998.All of them were divided into three groups (normal group,OGTT group,GDM group) and given 75g OGTT.Results Positive 50g GST correlated greatly with abnomal OGTT;Women with positive 50g GST who had high risk factors had significantly high rates of abnomal OGTT.The accidental rates of GDM rose with significantly high in the woman of 50g GST≥10mmol/L;abnomality of 75g OGTT had no relationship with gestational time,during the first timester 27.3% GDM were diagnosed.Conclusion 50g GST was very important to GDM diagnosis,especially to women who had high risk factors.