摘要
目的探讨18F-FDGPET/CT在诊断不明原发灶肿瘤(CUP)患者原发灶中的价值。资料与方法36例CUP患者行PET/CT检查拟寻找原发灶,根据转移灶部位分为淋巴结转移组(8例)、肝转移组(9例)、骨转移组(12例)及恶性胸腹水组(7例),比较18F-FDGPET/CT诊断淋巴结转移组与非淋巴结转移组CUP患者原发灶的灵敏度。结果 18F-FDGPET/CT寻找CUP原发灶的灵敏度为63.9%(23/36),PET/CT诊断淋巴结转移组、肝转移组、骨转移组及恶性胸腹水组患者原发灶的灵敏度分别为87.5%(7/8)、55.6%(5/9)、58.3%(7/12)、57.1%(4/7)。18F-FDGPET/CT对淋巴结转移组原发灶的确诊率[87.5%(7/8)]显著高于非淋巴结转移组[57.1%(16/28)],差异有统计学意义(P<0.05)。结论 18F-FDGPET/CT诊断CUP患者原发灶灵敏度较高,尤其适用于发生淋巴结转移的CUP患者。
Purpose To explore the value of 18 F-FDG PET/CT in the diagnosis of primary focus for patients with carcinoma of unknown primary （CUP）.Materials and Methods Thirty-six patients with CUP underwent PET/CT to detect the primary focus,and further divided into lymph node metastasis group （n=8）,liver metastasis group （n =9）,bone metastasis group （n=12）,malignant hydrothorax and ascites group （n=7） according to sites of metastasis.The sensitivity of diagnosing primary focus in patients with CUP between lymph node metastasis group and nonlymph node metastasis group using PET/CT was analyzed.Results The sensitivity of 18 F-FDG PET/CT in detecting primary focus for patients with CUP was 63.9% （23/36）,the sensitivities in lymph node metastasis group,liver metastasis group,bone metastasis group,malignant hydrothorax and ascites group were 87.5% （7/8）,55.6% （5/9）,58.3% （7/12）,57.1% （4/7）,respectively.The diagnostic rate in lymph node metastasis group [87.5% （7/8）] was statistically higher than that of non-lymph node metastasis group [57.1% （16/28）] （P〈0.05）.Conclusion 18 F-FDG PET/CT is sensitive to diagnose the primary focus for patients with CUP,especially for patients with lymph node metastasis.
出处
《中国医学影像学杂志》
CSCD
北大核心
2012年第6期468-470,共3页
Chinese Journal of Medical Imaging
