榼藤藤茎醋酸乙酯部位化学成分的研究

Constituents from ethyl acetate extract from canes of Entada phaseoloides

目的对榼藤Entada phaseoloide藤茎醋酸乙酯部位的化学成分进行研究。方法综合运用硅胶、反相硅胶RPC18、SephadexLH-20等色谱法进行分离,NMR、MS等波谱学方法进行结构鉴定。结果从榼藤藤茎甲醇提取物的醋酸乙酯萃取部位中分离得到了11个化合物,通过波谱分析鉴定为表没食子儿茶素没食子酸酯(1)、表儿茶素没食子酸酯(2)、落新妇苷(3)、木犀草素(4)、(?)-表儿茶素(5)、甘草苷(6)、β-香树脂醇(7)和日耳曼醇(8)的混合物、没食子酸(9)、β-谷甾醇(10)、胡萝卜苷(11)。结论所有化合物均为首次从榼藤中分离得到,其中化合物1～9在榼藤子属植物首次报道。

Objective To study the chemical constituents from ethyl acetate extract from canes of Entada phaseoloides.Methods The compounds were separated and purified by column chromatography on silica gel,RP C18,and Sephadex LH-20,and were identified by MS and NMR.Results Eleven compounds were isolated from the ethyl acetate fraction in methanol extract from canes of E.phaseoloide,and their structures were elucidated as epi-gallocatechin gallate（1）,epicatechin gallate（2）,astilbin（3）,luteolin（4）,（？）-epicatechin（5）,liquiritin（6）,mixture of β-amyrin（7） and germanicol（8）,gallic acid（9）,β-sitosterol（10） and daucosterol（11）.Conclusion Compounds 1—11 are isolated from this plant for the first time.Compounds 1—9 are firstly reported in the plants of Entada Adans.