北京协和医院痛风门诊患者数据库的资料分析

Clinical analysis of gout outpatient database from Peking Union Medical College Hospital

目的对痛风门诊的痛风患者进行临床资料总结和临床特点分析。方法对2008年1月-2012年3月间就诊于北京协和医院痛风门诊的358名痛风患者进行问卷调查和临床资料收集,检测血生化指标,将以上资料录入数据库系统并进行数据导出和分析,以了解该人群的临床特点。结果患者中男性350例(97.8%),女性8例(2.2%),平均病程(99.5±76.9)月,血清尿酸平均值(586±123)μmol/L,多关节受累79%;77例(21.5%)合并痛风石,痛风石常见部位依次为双手关节、跖趾关节和耳廓,基础疾病合并率71.5%。结论中青年痛风患者为多,多关节受累,基础疾病合并率高,临床特征多样化、复杂化。

Objective Analyse the clinical characteristic of gout outpatients from Peking Union Medical College Hospital. Methods Questionnaire survey and clinical analysis was conducted to collect and analyse 358 gout outpatients＇ clinical data and feature. Results The proportions of males and females were 97. 8% and 2. 2% re- spectively. Among the 358 patients with the average duration of （ 100. 1 ± 76. 7） months and mean serum uric acid level of （601.49 ± 11.16）μmol/L, multi-joints affected patients accounted for 79%. Tophus was found in 77 （21.5%） p＇aitents, and tophus affected hands, metatarsophalangeal joints and auricle. 71.5% had coexistence of basic diseases. Conclusions Young and middle-aged patients are in the majority. Most patients have multi-joins af- fected with a highrate of underlying disorder coexisting. Clinical presentation is diversified and complicated.