声触诊组织量化技术评估组织硬度的影响因素分析

Study of influential factors in evaluating tissue stiffness by virtual touch tissue quantification

目的探讨声触诊组织量化技术中深度和介质因素对组织硬度测量值的影响。方法选用猪的4种离体组织，其中3种作为介质（脂肪、肌肉和肝），3种作为被测物体（肾、肝和肌肉），取2cm、3cm、4cm和5cm4种测量深度，分别测量3种物体在不同深度不同介质下的剪切波速度（Vs）值。结果将深度2、3cm的Vs值作为一组，4、5cm的Vs值作为一组，两组Vs值差异有统计学意义，且深度越大物体Vs值越小。不同介质下物体Vs值之间差异也有统计学意义。结论利用声触诊组织量化技术评估组织硬度时，不同测量深度及介质对物体弹性测量值存在影响。

Objective To investigate the influence of different depths and mediums on tissue stiffness measurement by virtual touch tissue quantification technology. Methods Four kinds of in vitro porcine tissue were recruited,three （fat, muscle and liver） were assigned as medium group and three （kidney, liver and muscle） as sample group. The shear wave velocity （Vs） of the samples was measured under different mediums and at different depths （2 cm,3 cm,4 cm and 5 cm） ,respectively. Results According to the depth of measurement,two groups of Vs were defined with one group at the depth of 2 cm and 3 cm while the other at 4 cm and 5 cm. The difference of Vs between the two groups was of statistical significance and with the increase of the depth Vs values decreased. Even at the same depth,the differences of Vs under different mediums were statistically significant. Conclusions Depths and mediums have great influence on evaluating elasticity measurements by virtual touch tissue quantification technology.