新生儿医院感染及抗菌药物使用情况分析

The analysis of nosocomial infection and antibiotics usage in hospitalized neonates

目的探讨医院新生儿科发生医院感染的高危因素,调查某医院新生儿科抗菌药物使用情况。方法抽取2011年6月至12月新生儿住院病历426例做回顾性分析。结果住院新生儿的医院感染高危因素分别为:男性、早产儿、低出生体重儿、吸入综合征、新生儿窒息、羊水污染、重症监护、气管插管、长时间住院、预防应用抗菌药物。抗菌药物使用率较高、细菌培养率和药敏试验率达不到要求、预防用药过多。结论该院新生儿使用抗菌药物尚存在不合理现象,应加强培训和管理,督促临床医生合理应用抗菌药物。

Objective To identify risk factors,incidence and trends of nosoeomial infections.To investigate the application of antimicrobial agents in the neonate ward.Methods All medical records of neonate who were discharged from June to December 2011 were reviewed.Results The main risk factors of nosoeomial infections are premature birth,low birth weight,asphyxia,inhalation syndrome ICU admission,tracheal intubation,prolonged hospitalization and prophylactic antibiotics usage.Clinical use of antimicrobial agents were still some areas to be improved：control the use of antibiotics and sensitivity test was mainly and use too much prophylactic antibiotics.Conclusion There are irrational phenomena in the application of antimicrobial agents in the neonate ward of this hospital,the management and education about rational use of antimicrobial agents must be strengthened among clinical doctors.