三拗汤滴丸的成型工艺研究

Formation technology of Sanaotang Drop Pills

目的优化三拗汤滴丸的制备工艺。方法以滴丸的成型、圆整度、滴距、滴速、基质与药物比为主要考察因素,对三拗汤滴丸的制备进行优化。结果最佳工艺条件为药物与基质比为1:3,滴距为4cm,温度75℃。结论此方法制备工艺简单、操作方便,制得的滴丸丸重差异小、综合质量好,符合滴丸的质量要求,可以用于三拗汤滴丸的制备。

Objective To optimize the formation technology for Sanaotang Dropping Pills （SDP）. Methods To choose the molding, roundness, dropping distance, dropping speed, and ratio of the matrix to the drugs as main factors, the best method to make SDP was optimized. Results The optimum technology condition was as follows： The ratio of matrix to drugs was 1：3, the dropping distance was 4 cm, and the temperature was 75 ℃. Conclusion The method is simple and covenient, and SDP with low pill weight variation and good quality could be produced under the conditions.