益气活血通络方治疗冠心病心绞痛30例临床观察

Therapeutic Effect of Yiqi HuoxueTongluo Decoction for Angina Pectoris in Patient with Coronary Heart Disease

目的:观察益气活血通络方对冠心病稳定性心绞痛气虚血瘀证患者血浆同型半胱氨酸(Hcy)、超敏C反应蛋白(hs-CRP)及生活质量的影响。方法:将60例患者随机分为2组各30例,对照给予西医基础治疗,治疗组在对照组治疗基础上加服益气活血通络方。结果:治疗组治疗后Hcy、hs-CRP水平明显降低(P<0.05,P<0.01),治疗组在改善患者Hcy、hs-CR P优于对照组(P<0.05);患者Seattle Angina Questionnaive(SAQ)评分比较,2组在治疗满意度及疾病认识程度无显著差异外,其他各项及总分治疗组均优于对照组(P<0.05)。结论:益气活血通络方联合西医基础治疗冠心病稳定性心绞痛气虚血瘀证疗效优于西医基础治疗。

Objective. To observe the effect of Yiqi Huoxue Tongluo Decoction on plasma homocysteine （Hcy）, high-sensi- tivity C-reactive protein（hs-CRP）, and quality of life （QOL） in Qi-deficiency and blood-stasis stable angina pectoris with coro- nary heart disease. Methods= Sixty patients were equally randomized into treatment group and control group. The two groups were given routine western medicine, and the treatment group was given oral use of Yiqi Huoxue Tongluo Decoction. Results= After treatment, serum Hcy and hs-CRp levels were decreased in the two groups（P 〈 0.05 or P 〈 0.01）, and the decrease in the treatment group was superior to that in the control group（P 〈 0.05）. As for Seattle Angina Questionnaire （SAQ） scoring, treatment group has higher total score and scores of items except for the satisfaction and cognition degree of disease （P 〈 0.05）. Conclu- sion= Yiqi Huoxue Tongluo Decoction combined with routine western medicine has better curative effect for treatment of Qi-de- ficiency and blood-stasis stable angina pectoris with coronary heart disease than routine western medicine alone.