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脱乙酰壳多糖支架在牙周组织工程中的应用 被引量：1

Application of chitosan scaffolds in periodontal tissue engineering
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摘要 脱乙酰壳多糖生物材料尽管具有良好的生物相容性,但其作为牙周组织工程支架材料时也有自身的局限和不足。本文就牙周组织工程、脱乙酰壳多糖、脱乙酰壳多糖牙周组织工程支架等研究进展作一综述。 Although chitosan possesses excellent bioeompatibility, there are some disadvantages when it is used in periodontal tissue engineering. This present article is to review the higher researching value and better promising clinical utilization of chitosan complex scaffolds in periodontal tissue engineering.
作者 张庆鸿 梁星
机构地区 浙江大学医学院附属口腔医院修复科 四川大学华西口腔医院修复科
出处 《国际口腔医学杂志》 CAS 2012年第4期476-478,共3页 International Journal of Stomatology
基金 浙江省自然科学基金资助项目(Y2080340)
关键词 牙周病 牙周组织 牙周组织工程 脱乙酰壳多糖 支架 牙周膜细胞 periodontal disease periodontal tissue periodontal tissue engineering ehitosan scaffold pe- riodontal ligament cell
分类号 R783.1 [医药卫生—口腔医学]
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参考文献15

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同被引文献15

  • 1Shu-Yao Tsai,Yuan-Li Huang,Wei-Hung Yang,Chih-Hsin Tang.Hepatocyte growth factor-induced BMP-2 expression is mediated by c-Met receptor, FAK, JNK, Runx2, and p300 pathways in human osteoblasts[J].International Immunopharmacology.2012(2)
  • 2Sungwoo Kim,Yunqing Kang,Chad A. Krueger,Milan Sen,John B. Holcomb,Di Chen,Joseph C. Wenke,Yunzhi Yang.Sequential delivery of BMP-2 and IGF-1 using a chitosan gel with gelatin microspheres enhances early osteoblastic differentiation[J].Acta Biomaterialia.2012(5)
  • 3BinShi,XiangrongCheng,YufengZhang.Enhanced bone regeneration around dental implant with bone morphogenetic protein 2 gene and vascular endothelial growth factor protein delivery[J].Clinical Oral Implants Research.2012(4)
  • 4LudmilaLuca,Anne‐LaureRougemont,Beat H.Walpoth,LudovicBoure,AndreaTami,James M.Anderson,OlivierJordan,RobertGurny.Injectable rhBMP‐2‐loaded chitosan hydrogel composite: Osteoinduction at ectopic site and in segmental long bone defect[J].J Biomed Mater Res.2010(1)
  • 5Ludmila Luca,Anne-Laure Rougemont,Beat H. Walpoth,Robert Gurny,Olivier Jordan.The effects of carrier nature and pH on rhBMP-2-induced ectopic bone formation[J].Journal of Controlled Release.2010(1)
  • 6Halil Ibrahim Canter,Ibrahim Vargel,Petek Korkusuz,Filiz Oner,Dilsad B. Gungorduk,Barbaros Cil,Erdem Karabulut,Mustafa F. Sargon,Yucel Erk.Effect of Use of Slow Release of Bone Morphogenetic Protein-2 and Transforming Growth Factor-Beta-2 in a Chitosan Gel Matrix on Cranial Bone Graft Survival in Experimental Cranial Critical Size Defect Model[J].Annals of Plastic Surgery.2010(3)
  • 7Xufeng Niu,Qingling Feng,Mingbo Wang,Xiaodong Guo,Qixin Zheng.Preparation and characterization of chitosan microspheres for controlled release of synthetic oligopeptide derived from BMP-2[J].Journal of Microencapsulation.2009(4)
  • 8Shi, Zhilong,Neoh, K.G.,Kang, E.T.,Chye, Khoon Poh,Wang, Wilson.Surface functionalization of titanium with carboxymethyl chitosan and immobilized bone morphogenetic protein-2 for enhanced osseointegration[].Biomacromolecules.2009
  • 9F. Milone,C. Pivonello,F. Cariati,M. Sarnataro,V. Ramundo,V. Marotta,H. Jann,U.-F. Pape,B. Wiedenmann,A. Colao,M. Pavel,A. Faggiano.Assessment and clinical implications of RANK/RANKL/OPG pathway as markers of bone tumor progression in patients with NET harboring bone metastases[].Biomarkers.2013
  • 10Pregizer Steven,Barski Artem,Gersbach Charles A,García Andrés J,Frenkel Baruch.Identification of novel Runx2 targets in osteoblasts: cell type-specific BMP-dependent regulation of Tram2[].Journal of cellular biochemistry.2007

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国际口腔医学杂志
2012年 第4期

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