黄柏饮片与煮散颗粒在不同煎煮时间点盐酸小檗碱含量和干膏收率的比较

Comparison of Changes of Content of Berberine Hydrochloride and Yield of Dry Extract from Pieces and Powder of Phellodendri chinense in Different Boiling Time

目的:比较黄柏饮片与煮散颗粒在不同煎煮时间点盐酸小檗碱含量和干膏收率的变化。方法:采用HPLC测定黄柏饮片和煮散颗粒在不同煎煮时间点煎液中盐酸小檗碱含量,同时测定不同煎煮时间点煎液中的干膏收率。结果:煎煮5～60 min时,不同时间点黄柏煮散颗粒煎液中的盐酸小檗碱含量及干膏收率均高于黄柏饮片煎液,差异均有极显著性(P<0.01)。结论:本试验验证了中药煮散省材省时之优点,以期为中药传统饮片应用形式的创新提供新思路。

Objective： To compare changes of content of berberine hydrochloride and yield of dry extract between pieces and powder of Phellodendri chinense in different boiling time. Method： HPLC was used to determine the content of berberine hydrochloride and yield of dry extract from decoction of pieces and powder of P. chinense at different decoction time. Result： The content of berberine hydrochloride and yield of dry extract in powder were both greatly more than they were in pieces of P. chinense during 5-60 min, there was a significant difference （P 〈0.01 ）. Conclusion： This study verified that Chinese medicine decoction had advantages of time- saving and energy-saving, in order to provid new ideas for application form innovation of traditional Chinese medicine pieces.