方证相应的寒热证动物模型研究进展

Research on Animal Models of Cold and Heat Syndrome Based on Corresponding of Formulas and Syndromes

对方证相应寒热证动物模型研究进展的文献进行整理和分析。以寒热证动物模型、方证相应为关键词,检索了近20年中国知识资源总库,得到相关文献229篇,逐篇阅读、甄别、梳理和选择。采纳参考文献19篇。以方致证的寒热证动物模型,有采用温热方剂制作热证动物模型,也有采用寒凉方剂制作寒证动物模型。其他方法致寒热动物模型及以方治证,有采用灌服冰水、干辣椒粉等方法致脾胃寒热证动物模型,并治以理中丸、大黄黄连泻心汤等温热、寒凉方剂,也有肠热证动物模型治以大承气汤,湿热证动物模型治以加味四妙散等。寒热证动物模型及方证相应的报道虽多,但有待上升到较统一的认识;建立准确的寒热证动物模型,进行方证相应的研究,须找到可供观察的特异性客观指标;在观察和评价寒热证的时候,要重视体质因素;可尝试用寒热偏性的方剂制作寒证热证动物模型,然后选用寒热偏性的方剂进行治疗。

Collation and analysis of the research on animal models of cold and heat syndrome based on the corresponding of formulas and syndromes . Animal models of cold and heat syndrome, corresponding of formulas and syndromes as keywords. Retrieval the CNKI for nearly 20 years , find 229 literature, by - chapter reading, screening, sorting out and choosing. The adoption of the reference for 19.. Animal models of cold and heat syndrome caused by formulas, using heat syndrome animal models to product the warm prescription, using cold syndrome animal models to product the cold prescription. The animal models of cold and heat syndrome caused by other means , stomach cold and heat syndrome animal model caused by the ice water, dried chili powder and so on , using the warm, cold prescription as Lizhong pill, Dahuang Huanglian Xiexin decoction to treat. Intestinal heat syndrome animal model treated by Dacheng Qi decoction, Damp -heat syndrome animal model treated by Modified Simiao Powder. The reports about animal models of cold and heat syndrome and the corresponding of formulas and syndromes are numerous, but it is necessary to be up to a more uniform understanding; we should find the specific observation of objective indicators to establish an accurate animal models of cold and heat, and research the corresponding of formulas and syndromes; in the observation and evaluation of the cold and heat syndrome, we should pay attention to physical factors; we also can try to establish animal models of cold and heat syndrome by given the formulas with cold or heat in nature, then treat with proof by contradiction of formulas with cold or heat in nature.