慢性酒精中毒患者的临床特点与神经电生理分析

Nerve electrophysiology analysis of chronic alcoholic patients

目的:研究慢性酒精中毒患者其周围神经病变的临床特点及神经电生理检测分析。方法:对80例慢性酒精中毒患者检测其正中神经、胫神经、腓总神经的运动神经传导速度(MCV)及F波,胫神经、正中神经、尺神经的感觉神经传导速度(SCV)及F波,与78例无饮酒嗜好的健康人作对照分析。结果:80例慢性酒精中毒的MCV下降异常率为65.6%,SCV下降异常率为81.8%。与对照组比较差异有统计学意义(P<0.01),SCV受累较MCV重。神经电生理检测的异常可早于临床症状。结论:神经电图检测能早期诊断慢性酒精中毒及指导治疗。

Objective： To explore clinical and electrophysiological features of patients with chronic alcoholism peripheral neuropathy. Methods. The median nerve, tibial nerve, common peroneal nerve motor nerve conduction velocity （ MCV ） and F wave, tibial nerve, median nerve, ulnar nerve sensory nerve conduction velocity （ SCV ） and F wave were detected in 80 patients with chronic alcoholism and 78 healthy control subjects without alcohol addiction, Results were compared. Results： In 80 patients with chronic alcoholism MCV decreased, the abnormal rate was 65. 6%, SCV also decreased, the abnormal rate was 81.8%,showing significant difference comparing with that of the control group （P〈0.01）, SCV were more severely affected than MCV. Neural electrophysiological abnormalities can be detected earlier than presence of clinical symptoms. Conclusion： Nerve electrogram detection is helpful for early diagnosis of chronic alcoholism and can guide clinical treatment.