颅内动脉瘤患者相关因素对开颅手术预后的影响分析

Effect of related factors on prognosis of intracranial aneurysm surgery

目的:探讨影响颅内动脉瘤开颅手术预后的相关因素,以期用来指导临床治疗。方法:分析我院自2005年6月～2011年12月收治的412例颅内动脉瘤开颅手术患者资料,统计分析年龄、性别、血糖、血压、Fisher's分级、手术时机、Hunt-Hess分级、白细胞升高程度、脑血管痉挛(cerebral vasospasm,CVS)、感染等因素对患者预后的影响程度。结果:CVS、Fisher's分级、Hunt-Hess分级、白细胞升高程度、感染是影响此类患者开颅手术预后的相关因素(P<0.01),Hunt-Hess分级与开颅手术预后呈线性负相关关系。结论:动脉瘤的开颅手术预后受多种因素影响,明确影响动脉瘤开颅手术预后的相关因素并采取相应措施,能提高动脉瘤的手术治疗效果。

Objective. To investigate the impact factors on prognosis of intracranial aneurysm sur- gery and improve the prognosis of patients with intracranial aneurysms. Methods： Data of 412 cases with intracranial aneurysms underwent surgery from June 2005 to December 2011 were analyzed, including age, gender, blood sugar, blood pressure, Fisher＇s grading, operation time, Hunt-Hess grading, cerebral vaso- spasm（CVS）, the increased degree of WBC and infection incidence. Results： CVS, Fisher＇s grading, Hunt- Hess grading, the increased degree of WBC and infection were the factors related to the outcomes of pa- tients （P〈0.01）. Hunt-Hess grading was in negative correlation with prognosis. Conclusions.The prog- nosis of surgery is affected by various factors. It need appropriate analysis and in time measures to improve prognosis.