机关工作人员脂肪肝与体型、血脂的相关分析

Correlation among fatty liver、obesity and dyslipidemia in staff of government division

目的:了解脑力劳动者脂肪肝的发生情况,探讨该人群脂肪肝与高血脂、体重指数(BMI)、腹型肥胖的相关性。方法:整群选取2010年8月在我院体检的脑力劳动者1 244名,测量其身高、体重、腰围(WC)、臀围,并进行肝脏B型超声检查和血脂、血清丙氨酸氨基转移酶(ALT)、血糖的测定。结果:(1)脂肪肝总检出率为32.1%,男性肥胖、超重、体重正常组脂肪肝检出率分别为86.3%、51.7%和17.3%;女性肥胖、超重、体重正常组脂肪肝检出率分别为56.5%、44.2%、4.0%,组间差异均有统计学意义(P均<0.01)。(2)脂肪肝组WC、腰臀比(WHR)、收缩压(SBP)、舒张压(DBP)、甘油三酯(TG)、血清总胆固醇(TC)、空腹血糖(FPG)、ALT水平显著高于非脂肪肝组,差异均有统计学意义(P<0.05)。(3)脂肪肝检出率与血脂成分有关,混合型高脂血症组的检出率>单纯性高TG组>单纯性高TC组,组间差异有统计学意义(P<0.05)。(4)同一体重指数分组中腹型肥胖脂肪肝检出率高于非腹型肥胖组,组间差异有统计学意义(P<0.05)。结论:脂肪肝的发生与体重指数、血脂呈正相关;甘油三酯与脂肪肝的发生密切相关,腹型肥胖者发生脂肪肝的危险性显著高于正常腰臀比者。

Objective： To explore the prevalence of fatty liver in adult brainworkers and the correlation of fatty liver with hyperlipidemia, blood glucose, BMI and abdominal obesity. Methods： A cluster sampling was conducted in Beijing ShiJitan Hospital in August 2010. Height, weight, waist circumference （WC）, hip circumference, liver ultrasound B scans, serum lipids and ALT and fasting glucose were detected in 1244 adult brainworkers. Results： The prevalence of fatty liver was 32.1%. The rate of fatty liver in obese group, overweight group and normal weight group were 86.3%, 51.7% and 17.3% ,respectively in men, and the rate of fatty liver in women of the three group were 56.5%, 44.2% and 4.0% showing significant difference among groups （P〈0.05）. The level of WC, WHR, SBP, DBP ,triglyceride （TG）, total cholesterol （ TC ） , blood glucose and ALT in patients with fatty liver were significantly higher than those in non- fatty liver group （P〈 0.05）. The detection rate of fatty liver in mixed hyperlipidemia group was higher than that in single hypertriglyceridemia group, and single hypercholesterolemia group. The prevalence of fatty liver in abdominal obesity group was significantly higher than non-abdominal obesity （P 〈0.05）. Conclusion：The prevalence of fatty liver is positively correlated with BMI, serum lipids,abdominal obesity. Triglyceride level is key factor for prevalence of fatty liver. The risk of fatty liver in abdominal obesity is significantly higher than non-abdominal obesity.