笑气吸入应用于胃镜检查的临床效果观察

Effects of Nitrous Oxide Inhalation in Gastroscopy

目的观察笑气应用于胃镜检查的临床效果。方法笑气吸入下胃镜检查者103例(笑气组),常规胃镜检查者110例(对照组),观察患者胃镜操作时间,检查前、中、后血压,心率,血氧饱和度和胃镜检查中的反应及感受。结果笑气组患者咽部不适、恶心、呕吐和躁动的发生率低于对照组,差异均有统计学意义(P<0.05)。笑气组胃镜操作时间短于对照组(P<0.05)。笑气组检查前、中、后收缩压、舒张压及心率低于对照组,除检查前收缩压外,差异均有统计学意义(P<0.05);两组检查前、中、后脉搏血氧饱和度比较,差异均无统计学意义(P>0.05)。笑气组患者难以忍受、明显不适及轻微不适的例数均少于对照组,而无不适的例数明显多于对照组,差异有统计学意义(P<0.05)。结论笑气吸入应用于胃镜检查减少了患者的痛苦,增加了患者的依从性,并且操作简单,缩短了操作时间,减轻了胃镜检查对患者的刺激,值得临床推广。

Objectives To observe the clinical effect of nitrous oxide（NO） inhalation used in gastroscopy.Methods Time length of gastroscopy operation and blood pressure,heart rate（HR）,blood oxygen saturation were observed in 103 subjects receiving NO inhalation（NOI group） and 110 subjects receiving conventional gastroscopy（control group） before,during,after gastroscopy,and reaction and feeling during gastroscopy.Results Pharyngeal discomfort,nausea,vomiting and restlessness incidence were lower in NOI group than in control group,the difference was significant except restlessness incidence（P0.05）.The operational time length of NOI group was shorter than that of control group（P0.05）.Systolic pressure（SP）,diastolic pressure and HR before,during,after gastroscopy of NOI group were lower than that of control except SP before it（P0.05）.But there was not significant difference in blood oxygen saturation（P0.05）.The case number with unbearable and slight discomforts was fewer in NOI group than in control group,and cases without discomfort more,the difference was significant（P0.05）.Conclusion NO inhalation used in gastroscopy is worthy of clinical application.