摘要
目的:探讨血乳酸水平与感染性休克患者预后的关系。方法:58例感染性休克患者分为存活组和死亡组,动态监测血乳酸值及进行APACHEⅡ评分,比较上述指标的差异性。结果:①对照组、感染性休克患者存活组、死亡组治疗前动脉血乳酸水平分别为(0.63±0.33)mmol/L,(2.88±0.35)mmol/L,(7.54±0.66)mmol/L,感染性休克患者存活组血乳酸水平较对照组明显增高(P<0.05);死亡组血乳酸水平较存活组明显升高(P<0.05)。②感染性休克患者存活组血乳酸在48 h内达到正常,而死亡组患者的血乳酸明显高于存活组(P<0.05),随着血乳酸浓度的下降感染性休克患者的严重程度降低,生存率显著提高。③死亡组患者APACHEⅡ评分分值明显高于存活组(P<0.05),APACHEⅡ评分与血乳酸浓度显著正相关(r=0.674)。结论:血乳酸测定对于判断感染性休克患者病情预后具有重要价值。
Objective: To study the relationship between the blood lactic acidosis and prognosis of patients with septic shock. Methods: 58 cases of septic shock patients were divided into survival group and death group.Blood lactate levels and APACHE Ⅱ score were detected dynamically.All the difference were analyzed. Results: ①Before treatment,the lactic levels were(0.63±0.33) mmol/L in normal group,(2.88±0.35) mmol/L in survival group,and(7.54±0.66) mmol/L in death group respectively(P0.05).②The patient's blood lactic acid of survival gruoup becomed to normal in 48 h,the patient's blood lactic acid of died group was significantly higher than the survival group during a period of longer time(P 0.05).With the decline of the blood lactic acid density,the septic shock patients turned better,and the survival rate was significantly increased.③The APACHEⅡ score in death group was higher than that in survival group(P0.05),The APACHEⅡ score was positive correlated with blood lactic acid level(r=0.674). Conclusion: Blood lactic acid has an important value for the prognosis of the judgment in septic shock patients.
出处
《河南医学研究》
CAS
2012年第2期202-204,共3页
Henan Medical Research