2005-2010年郑州市腹泻病患者志贺病原菌检测

Detection for Shigella from diarrhea cases in Zhengzhou city from 2005 to 2010

目的:了解郑州市2005年至2010年志贺菌血清型别的变化。方法:依照《痢疾防治手册》开展志贺菌实验室检测。结果:共监测腹泻病患者2851例,检出志贺菌183株(6.42%),其中福氏菌145株(79.2%);宋内菌38株(占20.8%)。145株福氏菌中,F4c亚型55株(30.0%),F2a亚型39株(21.3%),F1a亚型36株(19.7%),F2b亚型6株(3.3%),Fx变种4株(2.2%),F4a亚型2株(1.1%),Fy变种1株(0.5%),F1b亚型1株(0.5%),F6亚型1株(0.5%);宋内Ⅰ型30株(16.4%),宋内Ⅱ型8株(4.4%)。结论:F4c亚型志贺菌为本市2005年和2006年菌株流行的优势菌株,2007至2010年逐渐被F2a亚型和宋内菌相取代。

Objective： To investigate the serotype distribution of Shigellosis Zhengzhou city from 2005 to 2010. Methods： According to the ＂Project for Surveillance of Shigellosis in China＂to carry out shigella bacteria laboratory testing. Results： 183 strains of shigella were isolated from 2851 diarrhea cases（6.65%）.Among them,145 strains were S.flexneri（145/183,79.2%） and 38 strains were S.sonnei（38/183,20.8%）.Among the 145 strains of S.flexneri,55 subtype were F4c（30.0%）,39 subtype were F2a（21.3%）,36 subtype were F1a（19.7%）,6 subtype were F2b（3.3%）,4 subtype were Fx（2.2%）,2 subtype were F4a（1.1%）,1 subtype were Fy（0.5%） and 1 strains were F6（0.5%）.Among the 38 strains of S.sonnei,30 strains were SⅠ.sonnei（16.4%） and 8 strains were SⅡ.sonnei（4.4%）. Conclusion： F4c was the major prevalence subtype（2005 and 2006）,F2a and S.sonnei was the major prevalence subtype and serotype（2007-2010）.