脑梗死rADC值变化与临床分期相关性的初步研究

Primary study on the relativity of rADC and the different stage of cerebral infarction

目的:分析脑梗死各临床分期的相对表现扩散系数(rADC)值变化,探讨rADC值的大小与临床分期的相关性。方法:收集22例脑梗死患者,分别于超急性期(<12h)、急性期(13～72h)、亚急性期(4～14d)、慢性期(15d)行常规序列和磁共振扩散加权成像(DWI)检查。测量各期病灶的ADC值,并计算rADC值,统计不同分期rADC值有无差异。按rADC值大小对临床各期病例进行统计,分析rADC值的大小与临床分期的相关性。结果:脑梗死rADC值在超急性期下降,急性期进一步下降;于亚急性期、慢性期逐渐上升。脑梗死病灶各期的rADC值有明显差异;脑梗死不同分期与rADC值大小有相关性。结论:根据脑梗死rADC值大小可判断其临床发病时间。

Objective： To analyze the change of relative ADC value in different stage of cerebral infarction and study the relativity of rADC and the stage. Methods： 22 patients with cerebral infarction were scanned with conventional sequences in different stage （hyperacute〈12 hours,acute 13-72 h,subacute 3-10 days and chronic 〉15 days）. The ADC values were measured on ADC mapping, rADC was calculated and statistically analyzed. The case was distributed according to the rADC val- ues. Analyzing correlation between the rADC and the time at brain infarction. Results： The rADC was depressed in the hyperacute stage,and depressed more in the acute stager it increased in the subacute and chronic stage gradually. There was significant difference in rADC of different stage. There was correlation between rADC and time. Conclusion： According to rADC,the stage of cerebral infarction was diagnosed accurately.