舒芬太尼联合丙泊酚用于无痛人流的临床观察

Clinical Observation of Sufentanil Combined with Propofol for Painless Artificial Abortion

目的:探讨舒芬太尼联合丙泊酚用于无痛人流的临床效果。方法:选择我院2009年9月至2011年2月妇产科门诊确诊的适合行人工流产术并且愿意结束妊娠的孕妇,随机将90例孕妇分为三组,即丙泊酚与舒芬太尼联合使用组(A组),丙泊酚与芬太尼联合使用组(B组),丙泊酚加生理盐水组(C组),三个组各30例,分析比较三组各项临床治疗指标。结果:三个组给药后2min的中心静脉压及心率较术前低,差异有统计学意义(P<0.05);A组患者使用量明显低于B组、C组,三组比较有统计学差异(P<0.05);A,B组术后腹痛发生率都较C组低,并且A组术后腹痛发生率较B组低,均有统计学意义(P<0.05)。结论:丙泊酚与舒芬太尼配伍应用于无痛人流的麻醉效果较好,起效迅速,安全平稳,不良反应少,适合在人流术中推广。

Objective： To investigate the sufentanil combined with propofol for painless clinical effects.Method： In our hospital from Sep.2009 to Feb.2011 for obstetrics and gynecology clinic diagnosed with artificial abortion and were willing to end pregnancy,pregnant women,90 cases of pregnant women were randomly divided into three groups,namely propofol combined with sufentanil group（A）,propofol and fentanyl in combination group（B group）,propofol plus saline group（C group）,three groups of 30 patients were analyzed and compared three groups of clinical indicators.Result： Three groups 2min after administration compared with the preoperative central venous pressure and heart rate low,the difference was statistically significant（P 0.05）;A group of patients was significantly lower than the B group,C group,three groups were statistically difference（P 0.05）;A,B group the incidence of postoperative pain are lower than the C group,and postoperative pain in group A than in group B the incidence of low,were statistically significant（P 0.05）.Conclusion： Propofol and sufentanil anesthesia for painless compatibility is good effect,rapid onset,safe and stable,with less adverse reactions,suitable for the promotion of abortion.