摘要
目的:探讨青春期多囊卵巢综合征的临床特征,提高早期诊断率以便早治疗。方法:35例青春期多囊卵巢综合征患者于月经周期第5天开始服用环丙孕酮加二甲双胍治疗3个周期,每周期21d。观察治疗前后患者的月经周期、BMI、痤疮、多毛情况,同时测定治疗前后的性激素以及胰岛素水平,并进行比较。结果:治疗后患者月经周期规律,F-G评分(4.3±3.7)、痤疮评分(1.1.±0.8)较治疗前的(7.9±2.4)、(3.4±1.4)有明显差异(P<0.05),LH(14.7±7.8)、FNS(8.9±4.5)、T(1.3±1.1)较治疗前的(20.7±12.8)、(12.9±4.1)、(2.9±0.7)有显著差异(P<0.05)。结论:环丙孕酮加二甲双胍能够有效地治疗青春期多囊卵巢综合征,青春期少女出现月经不调、多毛、痤疮等症状时,应当尽早进行相应检查,排除发病可能。
Objective: To explore the clinical features of adolescent polycystic ovary syndrome,in order to improve early diagnosis and early treatment.Method: 35 cases of polycystic ovary syndrome in adolescent from 5th days of the menstrual cycle to start taking cyproterone acetate + metformin for 3 cycles,21 days was a cycle.Result: After the treatment of menstrual cycle regularity than before,the score of F-G(4.3 + 3.7),acne score(1.1-0.8) than before treatment(7.9 + 2.4),(3.4 + 1.4) had significant difference(P 0.05),LH(14.7 + 7.8),FNS(8.9 + 4.5),T(1.3 + 1.1) than before treatment(20.7 + 12.8),(12.9 + 4.1),(2.9 + 0.7) had significant difference(P 0.05).Conclusion: Dolescent girls appear abnormal menstruation,hirsutism,acne and other symptoms,should be performed early corresponding examination.
出处
《河北医学》
CAS
2012年第7期938-940,共3页
Hebei Medicine
关键词
多囊卵巢综合征
青春期
环丙孕酮
二甲双胍
Polycystic ovary syndrome
Adolescence
Cyproterone acetate
Metformin