天麻素联合倍他司汀治疗后循环缺血的疗效

Treatment of Posterior Circulation Ischemia with Gastrodin and Betahistine

目的观察天麻素联合倍他司汀治疗后循环缺血的疗效观察。方法将80例后循环缺血患者按随机数字表法分为治疗组和对照组,每组40例。治疗组应用天麻素注射液0.6 g稀释后+倍他司汀氯化钠注射液500 mL(含倍他司汀20 mg),静脉滴注;对照组给予丹参注射液20 mL稀释后静脉滴注,2组均1次.d-1,疗程10 d,其他常规和对症处理也相同。治疗前后行经颅多普勒(TCD)检测椎-基底动脉收缩期峰值流速(Vp),观察不良反应发生情况并进行临床疗效评定。结果治疗组和对照组总有效率比较,差异有统计学意义(95.0%vs 70.0%,P<0.01);TCD显示治疗组血流速度的改善优于对照组(P<0.05)。结论天麻素联合倍他司汀治疗后循环缺血有效、安全。

Objective To observe the curative effect of gastrodin combined with betahistine on posterior circulation ischemia. Methods Eighty patients with posterior circulation ischemia were randomly divided into two groups, with 40 patients in each group. The treatment group was given intravenous drip infusion of 0.6 g gastrodin injection and 500 mL betahistine sodium chloride injection （containing 20 mg betahistine）. The control group was intravenously infused with 20 mL salvia injection. Intravenous drip infusion was given once a day for 10 days in both groups. Vertebro-basilar artery peak systolic velocity （Vp） was measured by transc-ranial Doppler （TCD） before and after treatment,and adverse reactions were recorded. Results Compared with control effective rate（95.0% vs combined treatment with group,treatment with gastrodin and betahistine significantly increased the total 70.0% ,P〈0.01 ）,and obviously improved the Vp gastrodin and betahistine is effective and safe for value （P〈0.05）. Conclusion The posterior circulation ischemia.