显微外科手术治疗颅脑肿瘤的临床研究

Clinical study of microsurgery in the treatment of craniocerebral tumors

目的探讨显微外科手术不同入路治疗颅脑肿瘤的临床途径和疗效分析。方法选取我院80例颅脑肿瘤患者,并根据其颅脑肿瘤病灶的部位不同分别采用不同手术入路行显微外科手术治疗,观察其临床疗效。结果本组80例颅脑肿瘤全切除74例,次全切除5例,大部切除1例;术后随访6～24个月均获良好预后,颅脑肿瘤原发临床症状基本消失,大部分患者均能够进行正常的学习和工作,无术后致残、生活不能自理等后遗症的发生;手术前后的生活质量评分差异有统计学意义(P<0.05)。结论显微外科手术治疗颅脑肿瘤应根据患者病灶的部位不同选择不同手术入路,能显著提高显微外科手术的临床疗效,改善患者预后,提高患者术后生活质量。

Objective To investigate the clinical pathways and curative effects of different approaches of microsurgery in the treatment of craniocerebral tumors. Methods 80 patients with craniocerebral tumors in our hospital were selected to receive different surgical approaches of microsurgical treatment according to the locations of lesions. Then the clinical curative effects were observed. Results Among the 80 patients with craniocerebral tumors, 74 patients received total resection, 5 patients received subtotal resection and 1 patient received major resection. After the 6 to 24 months of postoperative follow-up, good prognosis was obtained for all： primary clinical symptoms of craniocerebral tumors disappeared; most patients were capable of normal learning and work. No postoperative disabling, life disenabling or other sequelae were observed. The preoperative and postoperative scores of life quality were significantly different （P 〈 0.05）. Conclusion Choosing different surgical approaches of microsurgery according to the locations of lesions in the treatment of craniocerebral tumors can significantly enhance the clinical curative effects of microsurgery, improve prognosis of patients and promote postoperative life quality of patients.