尼立苏和尼莫通治疗脑梗塞的疗效比较

COMPARASON OF THE EFFECT OF NILISU AND NIMODIPINE IN TREATMENT OF CEREBRAL INFARCTION

目的 :比较尼立苏和尼莫通治疗脑梗塞的疗效及不良反应。方法 :70例脑梗塞患者随机分为 2组。尼立苏组 34例 ,用尼立苏注射液 10mg ,静滴 ,qd ;尼莫通组 36例 ,用尼莫通注射液 10mg ,静滴 ,qd。两组疗程均为 2周。结果 :治疗后d14尼立苏和尼莫通的有效率分别为 88 2 4%和 83 33% ,不良反应率分别为 14 7%和 13 88% ,均无显著性差异 (P >0 .0 5 ) ;两组的功能改善程度比较也无显著性差异 (P >0 .0 5 )。结论 :尼立苏是治疗脑梗塞的安全、有效的药物 。

OBJECTIVE: To compare the efficacy and safety of Nilisu and nimodipine in treatment of cerebral infarction METHODS: 70 patients with cerebral infarction were divided to receive Nilisu injection 10 mg/d for 2 weeks ( n =34) or nimodipine injection 10 mg/d for 2 weeks RESULTS: The effective rate were 88 24% for Nilisu group and 83 33% for nimotopine group The incidence rate of side effect was 14 75 for Nilisu group and 13.88% for nimodipine group. CONCLUSION: Nilisu is as effective s nimodipine in treatment of cerebral infarction