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nm23-H_1基因与非小细胞肺癌转移的关系

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摘要 目的探讨nm23-H1基因表达与非小细胞肺癌转移的关系。方法选择笔者所在医院2006年2月~2011年10月收治的肺癌手术患者46例,应用免疫组织化学SABC方法对46例NSCLC组织标本进行nm23-H1表达的检测。结果 46例NSCLC中nm23-H1过度表达为50%(23/46),其中鳞癌nm23-H1过度表达为47.62%(10/21),腺癌为58.33%(7/12),两者比较差异有统计学意义(P<0.05);nm23-H1的阳性表达与淋巴结转移呈负相关(P<0.01)。结论 nm23-H1可作为预测NSCLC淋巴结转移及预后的指标。
作者 周霖
出处 《中国医药科学》 2012年第12期36-37,共2页 China Medicine And Pharmacy
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