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多西他赛联合顺铂一线治疗肺腺癌术后临床效果观察 被引量:2

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摘要 目的:探讨抗代谢类抗癌药多西他赛联合顺铂(DDP)对术后肺腺癌的化疗方案疗效和不良反应.方法:将肺腺癌患者102例随机分为培美组55例,多西组47例,培美组将培美曲塞500 mg/m2加人NaCl溶液100 ml中静脉滴注10~30 min第1天;DDP 75 mg/m2加人5%葡萄糖液250 ml中静脉滴注1 h,分第1~3天给药,每21天重复.多西组将多西他赛(DOC)75 mg/m2加入5%葡萄糖液250 ml中静脉滴注1 h,第1天;DDP用药剂量及时问同培美组.结果:多西组不良反应较少,老年患者在通常情况下能耐受.结论:3周剂量多西他赛联合顺铂一线治疗肺腺癌不良反应少,明显优于单纯药物治疗,值得大力推广.
作者 邓燎 李岩
出处 《吉林医学》 CAS 2012年第17期3632-3633,共2页 Jilin Medical Journal
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