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连续不卧床腹膜透析的慢性肾功能衰竭患者继发甲状旁腺功能亢进的相关因素 被引量:5

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摘要 目的探讨连续不卧床腹膜透析(continuous ambulatory peritoneal dialysis,CAPD)的慢性肾功能衰竭患者甲状旁腺素(parathyroid hormone,PTH)升高的相关因素。方法检测93例患者腹膜透析前后血红蛋白(Hb)、白蛋白(Alb)、血钙(Ca)、血磷(P)、肌酐(Scr)、PTH、总胆固醇(TC)、三酰甘油(TG)、碱性磷酸酶(ALP)、尿素氮(BUN)等生化指标,并将PTH是否大于300 pg/L分组,对PTH与Hb、Ca、P、Alb、ALP、BUN、Scr等指标的相关性进行多元逐步回归分析。结果腹膜透析患者的继发性甲状旁腺功能亢进发生率为67.7%,高PTH与贫血、营养状况有关。Ca、BUN、ALP是PTH升高的独立危险因素(P<0.05)。结论腹膜透析的患者普遍存在继发性甲状旁腺功能亢进,高血清Ca、高BUN、高ALP可能与甲状旁腺素升高相关。
出处 《广东医学》 CAS CSCD 北大核心 2012年第12期1737-1739,共3页 Guangdong Medical Journal
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