纳米ZnO粒子的溶胶凝胶制备及抗菌活性研究

Fabrication and antibacterial activity of ZnO nano particles through Sol-gel method

采用溶胶凝胶法制备了纳米ZnO粒子,通过XRD、SEM对所制备粉体颗粒的物相组成以及表面形貌进行表征,并且通过K-B纸片扩散法研究了抗菌性能,并对比了紫外光照前后的抗菌性能.结果表明,所制备的ZnO纳米粒子粒径约为200nm左右,显示优良的抗菌活性,未经紫外光照对大肠杆菌(Escherichia coli)和金黄色葡萄球菌(Staphylococcus aureus)的抑菌圈达到18～22mm,并对其机理做了初步探讨.

ZnO nano particles were fabricated through sol-gel method. The phase, the crys- tallographic structure and the surface topography of the ZnO were charactered by XRD and SEM. The antibacterial activities of the ZnO paticles before and after ultraviolet irradiation were performed by the K-B disk diffusion method. The results show that the ZnO nano par- ticles prepared with sizes about 200 nm display great antibacterial activity, which show strong antibacterial activity with inhibition zone diameter of 18 to 22 mm against Escherichia coli and Staphylococcus aureus without ultraviolet irradiation. The mechanism of ZnO anti- bacterial activity is discussed.