感冒清口服液澄清工艺的研究

Study on Clarification Process of Ganmao-Qing Oral Liquid

目的:探索感冒清口服液最佳澄清工艺。方法:比较5种澄清工艺对感冒清口服液中总多糖含量、水浸出物的重量和外观澄清度,并对最佳工艺的作用条件进行了考察。结果:壳聚糖沉淀法对多糖含量影响较小,水浸出物的重量较低,外观澄清,效果较佳;壳聚糖用量为5%、溶液pH 5的条件下,澄清效果较好,残留量也较低。结论:壳聚糖沉淀法为感冒清口服液最佳澄清工艺。

Objective： To optimize the purification process of Ganmao-Qing oral liquid.Methods： By determining dry extract,total polysaccharide content and clarity degree,five clarification processs were compared.The optimum conditions were also investigated.Results： Chitosan adsorption technic had little influence on total polysaccharide content and could reduce the weight of dry extract.High clarity degree and low residue was achieved with 5%,chitosan solution at pH 5.Conclusion： Chitosan adsorption clarification technic can be used as the clarification process of Ganmao-Qing oral liquid.