柴防口服液辅助治疗小儿急性上呼吸道感染

Chaifang Oral Liquid as Supplementary Treatment for Children with Acute Upper Respiratory Infection

目的:观察柴防口服液治疗小儿急性上呼吸道感染的疗效。方法:将66例急性上呼吸道感染患儿随机分为治疗组(32例)和对照组(34例)。两组在常规治疗基础上,治疗组采用柴防口服液治疗,对照组采用利巴韦林治疗,疗程3 d。比较两组的体温变化及主要症状、体征的变化。结果:①治疗组平均退热时间[(2.8±1.3)]d短于对照组[(3.8±1.0)d](P<0.01);治疗组退热起效时间[(2.0±1.1)d]短于对照组[(2.8±1.1)d](P<0.01)。②体温疗效观察,治疗组总有效率84.4%;对照组总有效率64.7%(P<0.05)。③治疗后第5天两组患儿伴随症状比较,治疗组咽痛、咳嗽、流涕、鼻塞等症状完全缓解者多于对照组,其中治疗组咳嗽完全缓解者7例,对照组3例,有统计学差异(P<0.05)。结论:柴防口服液治疗小儿急性上呼吸道感染热证具有起效快、疗效好的特点,故可作为治疗小儿急性热证的首选药物之一,有着广泛的应用前景。

Objective ： To observe the clinical efficacy of Chaifang oral liquid in the treatment for children with fever of acute upper respiratory infection （AURI）. Method： Sixty-six qualified children with AUR1 were enrolled in this study and divided randomly into two groups： on the basis of conventional treatment, 32 cases were treated with Cha!fang oral liquid as Chinese medicine treatment group, 34 cases were treated with ribavirin as western medicine controll group. With 3 day course of treatment, patients were observed for changes in temperature, primary clinical symptoms and signs before and after treatment for comparing efficacy. Result：①Compared the temperature cooling time, the time of Chaifang oral liquid group was （2.8 ± 1.3） days, the time of controlled groupwas （3.8 ± 1.0） days, there is a statistical difference （P 〈 0.01 ）. The cooling start time （descended 0.5 ℃ by our standards） , that was （2.0 ± 1.1 ） days in Chaifang oral liquid group, the time in controlled group was （ 2.8 ± 1.1 ） days, there is a statistical difference （ P 〈 0. 01 ） ② In Chaifang oral liquid treatment group, the total efficacy of pyrexia extinction was 84.4%. In controll group, the total efficacy of pyrexia extinction was 64.7% , there is a statistical difference within two groups （P 〈 0.05）. ③ After treatment, patients were observed changes in clinical symptoms and signs, such as pharyngalgia, cough and stuffy nose, the rates of symptom disappearance in Chaifang oral liquid treatment group were higher than those in the control group, there is a statistical difference （ P 〈 0.05 ） for the cough disappearance rate.- Conclusion ： Chaifang oral liquid is better than Western medicine for body temperature cooling and it an effective prescription in the supplementary treatment deserves popularization in clinical practice. can markedly improve clinical symptoms and signs. It is for children with AURI. Thus, Chaifang oral liquiddeserves popularization in clinical practice.