正常胰腺及腹主动脉MSCT强化峰值和达峰时间与个体因素的相关性研究

Correlation of Peak Value and Peak Time of Normal Pancreas and Abdominal Aorta on Enhanced MSCT with the Individual Factors

目的:探讨正常胰腺及腹主动脉的强化峰值(PV)和达峰时间(PT)与年龄、性别及体质指数(BMI)的相关性,优化不同个体胰腺多期MSCT扫描时间窗的选择。方法:符合标准的62例患者分别进行MSCT胰腺灌注成像,并按年龄、性别及BMI分组,测量胰腺及腹主动脉的PV及PT值并按组别进行统计学分析。结果:①年龄组:44岁(包括44岁)以下组,正常胰腺PV值、PT值及腹主动脉PV值、PT值分别为(111.10±3.17)HU、(38.33±1.39)s、(343.22±17.65)HU、(31.08±1.41)s;45-59岁组,其参数值分别为(110.53±2.60)HU、(37.15±1.42)s、(357.88±12.29)HU、(30.62±1.43)s;60岁(包括60岁)以上组,其参数值分别为(116.67±4.27)HU、(36.92±1.95)s、(355.96±22.94)HU、(30.75±1.59)s。②性别组:男性组,正常胰腺PV值、PT值及腹主动脉PV值、PT值分别为(111.31±2.05)HU、(37.89±1.05)s、(341.28±9.19)HU、(30.83±0.96)s;女性组,其参数值分别为(113.92±4.10)HU、(36.53±1.52)s、(384.90±25.68)HU、(30.80±1.91)s。③BMI组:BMI值为22以下(包括22)组,正常胰腺PV值、PT值及腹主动脉PV值、PT值分别为(113.49±2.57)HU、(38.29±1.20)s、(371.89±12.88)HU、(31.31±1.17)s;BMI值为22以上组,其参数值分别为(109.94±2.56)HU、(36.63±1.28)s、(325.82±12.67)HU、(30.19±1.27)s。统计结果显示,腹主动脉PV值与BMI值有统计学意义(P<0.05),且呈负相关,其余各参数与年龄、性别及BMI值均无相关性。结论:除腹主动脉PV值随BMI值的增加逐渐降低外,其它参数受个体因素的影响小或不受影响。

Purpose： To explore the correlation between the peak value （PV） and peak time （PT） of normal pancreas and abdominal aorta, and age, gender and the body mass index （BMI）, and to optimize the choice of multi-phase CT scanning time window. Methods： Sixty-two patients, who had been undertaken multi-slices spiral CT perfusion imaging, were randomly chosen according to the inclusive criteria of normal pancreas and abdominal aorta. They were grouped according to their age, gender and BMI. In each group, the PV and PT of normal pancreas and abdominal aorta were measured respectively and the obtained data were statistically analyzed. Results： （1） Age Group： In the subgroup of patients with the age of 44 or below, the PV and PT of their normal pancreas and abdominal aorta were （lll.10＋3.17）HU and （38.33＋1.39）s, （343.22 ＋ 17.65）HU and （31.08＋ 1.41）s, respectively. In the subgroup of patients with the age between 45 and 59, the PV and PT of their normal pancreas and abdominal aorta were （110.53 ＋2.60）HU and （37.15_＋ 1.42）s, （357.88＋12.29）HU and （30.62＋1.43）s, respectively. In the subgroup of patients with the age of 60 or above, the PV and PT of their normal pancreas and abdominal aorta were （116.67＋4.27）HU and （36.92_＋1.95）s, （355.96_＋22.94）HU and （30.75_＋ 1.59）s, respectively. （2） Gender Group： In the subgroup of male patients, the PV and PT of their normal pancreas and abdominal aorta were （111.31_＋2.05）HU and（37.89_＋l.05）s, （341.28＋_9.19）HU and （30.83_＋0.96）s, respectively. In the subgroup of female patients, the PV and PT of their normal pancreas and abdominal aorta were （113.92_＋4.10）HU and （36.53_＋ 1.52）s, （384.90 ＋ 25.68）HU and （30.80_＋1.91）s, respectively. （3） BMI Group： In the subgroup of patients whose BMI was 22 or below, the PV and PT of their normal pancreas and abdominal aorta were （113.49＋2.57）HU and （38.29_＋1.20） s, （371.89_＋12.88）HU and （31.31＋1.17）, respectively. In the subgroup of patients whose BMI was over 22, the PV and PT of their normal pancreas and abdominal aorta were （109.94_＋2.56）HU and （36.63_＋1.28）s, （325.82_＋12.67）HU and （30.19_＋1.27）s, respectively. The analysis result indicated that statistical significant difference existed in the PV of abdominal aorta among the BMI sub-groups （P〈0.05） and BMI was negatively correlated with the PV of abdominal aorta. The other parameters had no correlation with age, gender and BMI. Conclusion： The PV of abdominal aorta is gradually decreased along with the increase of BMI. The other parameters are less or not influenced by the individual factors.