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光动力疗法在真菌感染性疾病中的应用 被引量：2

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摘要 光动力疗法（Photodynamic therapy，PDT）是一种光化学疗法，利用聚集于靶细胞内的光敏剂在低强度无害的可见光照射下产生的单线氧和氧自由基等活性因子杀死靶细胞。光敏剂可分为卟啉类、叶绿素类、染料类（如酞菁、萘酞菁）等，相比于第一代血卟啉衍生物（HpD），第二代、
作者 黄晓雯 席丽艳
机构地区 中山大学孙逸仙纪念医院皮肤科
出处 《皮肤性病诊疗学杂志》 2012年第3期186-188,共3页 Journal of Diagnosis and Therapy on Dermato-venereology
关键词 光动力疗法(PDT) 真菌 感染性疾病
分类号 R756 [医药卫生—皮肤病学与性病学]
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参考文献20

  • 1Wainwright M. Photodynamic therapy:the development of new photosensitisers[J].Anticancer Agents Med Chem,2008,(03):280-291.
  • 2Donnelly RF,McCarron PA,Tunney MM. Antifungal photodynamic therapy[J].Microbiological Research,2008,(01):1-12.doi:10.1016/j.micres.2007.08.001.
  • 3Giroldo LM,Felipe MP,de Oliveira MA. Photodynamic antimicrobial chemotherapy (PACT) with methylene blue increases membrane permeability in Candida albicans[J].Lasers in Medical Science,2009,(01):109-112.doi:10.1007/s10103-007-0530-2.
  • 4Smijs TG,Bouwstra JA,Schuitmaker HJ. A novel ex vivo skin model to study the susceptibility of the dermatophyte Trichophyton rubrum to photodynamic treatment in different growth phases[J].Journal of Antimicrobial Chemotherapy,2007,(03):433-440.
  • 5Smijs TG,Bouwstra JA,Talebi M. Investigation of conditions involved in the susceptibility of the dermatophyte Trichophyton rubrum to photodynamic treatment[J].Journal of Antimicrobial Chemotherapy,2007,(04):750-779.
  • 6Dovigo LN,Pavarina AC,Mima EG. Fungicidal effect of photodynamic therapy against fluconazole-resistant Candida albicans and Candida glabrata[J].Mycoses,2011,(02):123-130.
  • 7Dovigo LN,Pavarina AC,Ribeiro DG. Photodynamic inactivation of four Candida species induced by photogem[J].Brazilian Journal of Microbiology,2010,(01):42-49.
  • 8Bliss JM,Bigelow CE,Foster TH. Susceptibility of Candida species to photodynamic effects of photofrin[J].Antimicrobial Agents and Chemotherapy,2004,(06):2000-2006.doi:10.1128/AAC.48.6.2000-2006.2004.
  • 9Teichert MC,Jones JW,Usacheva MN. Treatment of oral candidiasis with methylene blue-mediated photodynamic therapy in an immunodeficient murine model[J].Oral Surgery,Oral Medicine,Oral Pathology,Oral Radiology & Endodontics,2002,(02):155-160.
  • 10Burki TK. Recent developments for cancer care in Africa[J].Lancet Oncology,2012,(01):e6.doi:10.1016/S1470-2045(11)70341-2.

同被引文献39

  • 1许德余,陈文晖,张浩,沈念慈.光动力治癌新药血卟啉单甲醚(HMME)的研究[J].中国激光医学杂志,1993,2(1):3-7. 被引量：60
  • 2王秀丽,王宏伟,过明霞,虞叶风,廖康煌.ALA光动力治疗鲍温样丘疹病临床研究[J].中国皮肤性病学杂志,2005,19(4):209-210. 被引量：19
  • 3Babilas P, Schreml S, Landthaler M, et al. Photodynamic therapy in dermatology: state-of-the-art[J].Photodermatol Photoimmunol Photomed, 2010, 26(3): 118-132.
  • 4Wehber J, Luo Y, Crilly R, et al. An apoptotic response to photodynamic therapy with endogenous protoporphyrin in vivo[J].J PhotochemPhotobiolB, 1996, 35(3): 209-211.
  • 5Huang Z.Photodynamic therapy in China: Over 25 years of unique clinical experience Part One-History and domestic photosensitizers[J]. PhotodiagnosisPhotodynTher, 2006, 3(1): 3-10.
  • 6Matei C, Tampa M, Poteca T, et al. Photodynamic therapy in the treatment of basal cell carcinoma[J].J Med Life, 2013, 6(1): 50-54.
  • 7魏振东,林茂,齐晓怡,等.5-氨基酮戊酸光动力疗法治疗日光性角化病26例临床观察//2013全国中西医结合皮肤性病学术年会论文汇编.2013:174.
  • 8Park KC, Kim KH, Youn SW, et al. Heterogeneity of human papillomavirus DNA in a patient with Bowenoid papulosis that progressed to squamous cell carcinoma[J].Br J Dermatol, 1998, 139(6): 1087-1091.
  • 9Stefanaki IM, Georgiou S, Themelis GC, et al. In vivo fluorescence kinetics and photodynamic therapy in condylomata acuminata[J].Br J Dermatol, 2003, 149(5): 972-976.
  • 10Morton CA, Szeimies RM, Sidoroff A, et al. European guidelines for topical photodynamic therapy part 1: treatment delivery and current indications - actinic keratoses, Bowen's disease, basal cell carcinoma[J].JEurAcadDermatolVenereol, 2013, 27(5): 536-544.

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皮肤性病诊疗学杂志
2012年 第3期

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