摘要
目的探讨老年维持性血液透析(MHD)患者死亡的病因,为提高老年MHD患者的生存率提供防治措施。方法收集2009年1月—2012年2月在上海长征医院及北站医院血透室接受MHD治疗的70例老年死亡患者的临床资料,分析其死亡原因、生存时间及死亡危险因素。结果老年MHD患者的前3位死亡原因分别为心血管疾病、感染、脑血管疾病。男性进入透析的平均年龄小于女性〔(71.6±8.9)岁vs(76.0±8.1)岁,P<0.05〕,但透析生存时间短于女性〔(34.1±53.9)月vs(63.2±65.1)月,P<0.05〕。透析生存时间与性别、清蛋白水平呈正相关,与心血管事件呈负相关,与脑血管事件及感染无相关性。结论积极改善患者的营养状况,防治心脑血管疾病、感染等并发症,适时开始血液透析可能有助于提高老年MHD患者的生存率。
Objective To explore the causes of death in elderly patients receiving maintenance hemodialysis (MHD) in order to find prevention and treatment measures to improve the survival rate of elderly MHD patients. Methods Clinical data of dead elderly patients who received MHD treatment in Shanghai Changzheng Hospital and Beizhan Hospital from January 2009 to February 2012 were collected. The causes of death, survival time and risk factors were analyzed. Results The top three causes of death for elderly MHD patients were cardiovascular disease, infections and cerebrovascular disease. The average age of men starting dialysis was younger than that of women [ (71.6 ±8.9) y vs (76.0 ±8. 1 ) y, P 〈0. 05], but the dialysis survival time of men was shorter than that of women [ (34. 1± 53.9) m vs (63.2 ± 65. 1 ) m, P 〈 0. 05 ]. Dialysis survival time was positively correlated with sex and albumin levels, but was negatively correlated with cardiovascular events, and was not correlated with cerebrovascular events and infections. Conclusion Improvement of nutritional status of patients, prevention and treatment of cardiovascular and cerebrovascular diseases, infections and other complications, timely start of dialysis are conducive to impro- ving the survival rate of patients.
出处
《中国全科医学》
CAS
CSCD
北大核心
2012年第18期2120-2122,共3页
Chinese General Practice