婴儿血管瘤的自然病程

Natural history of infantile hemangiomas

婴儿血管瘤是常见的血管性肿瘤，具有独特的生长周期，在婴儿期快速增生，接着缓慢退化。婴儿血管瘤在出生时不存在或不明显，但婴儿5个月时，血管瘤已完成大部分的增生，增生速率超过婴儿本身的生长速度。婴儿血管瘤通常4～7年完成退化，并遗留瘢痕。婴儿血管瘤不同于其他血管肿瘤和血管畸形，后者不会自然消退。概述婴儿血管瘤自然病程的研究进展，以增进对这种血管瘤生长特性和临床特征的认识。

Infantile hemangioma （IH） is a common vascular tumor with a unique lifecycle： rapid growth in infancy, followed by a period of involution, leading to a complete regression. IH is either absent or barely evident at birth,but usually completes its proliferative growth phase by 5 months of age. The growth rate of IH is characteristically beyond that of the infant. The involution phase of IH may take 4 to 7 years with residual scarring. The growth and involution of IH is very different from those of other vascular tumors and vascular malformations, which do not spontaneously regress. This review summarizes recent studies on natural history of IH, in order to promote a better understanding of hemangioma growth characteristics and clinical features.