新生儿高胆红素血症与先天性巨细胞病毒感染的相关性研究

The Research between the Hyperbilirubinemia in Newborns and Congenital Cytomegalovirus Infection

目的:探讨新生儿高胆红素血症与巨细胞病毒(HCMV)感染的相关性及临床意义。方法:对170例疑为高胆红素血症新生儿血清标本分别检测HCMV的IgG和IgM及血清总胆红素(TBIL)。排除高胆红素血症新生儿血清标本100例为正常对照。结果:高胆红素血症患者血清HCMV-IgG、IgM阳性率高于正常对照组,两者比较有统计学意义。结论:巨细胞病毒感染与新生儿高胆红素血症相关性大,是引起高胆红素血症的主要病原之一。

Objective： To investigate the relationship and its clinical significance between Neonatal hyperbilirubinemia and human cytomegalovirus infection.Methods： 170 cases of suspected neonatal hyperbilirubinemia serum specimens were detected by HCMV IgG and IgM and serum total bilirubin.Exclusion of neonates with hyperbilirubinemia serum specimens from 100 cases as normal con-trol.Results： The HCMV-IgG,IgM positive rate in the Patients with hyperbilirubinemia serum was higher than that of normal control group,there was significant difference between the two.Conclusion： Cytomegalovirus infection in newborn infants with hyperbilirubine-mia associated large,is one of the main pathogens causing hyperbilirubinemia.