期刊文献+

早期肠内营养对急性脑卒中伴Cushing溃疡患者的临床研究 被引量:4

下载PDF
导出
摘要 目的探讨早期肠内营养对急性脑卒中伴Cushing溃疡患者胃肠功能及预后的影响和效果。方法将95例急性脑卒中伴Cushing溃疡患者随机分为研究组与对照组,研究组49例,入院后24h后即给予鼻胃管肠内营养;对照组46例,禁食72h后再行肠内营养,入院后第7天检测胃液pH值及隐血实验,比较2组患者溃疡改善状况;比较21天的NIHSS、Barthel指数。结果研究组隐血实验阴性与胃液pH显着优于对照组;研究组的NIHSS显着优于对照组;两组的Barthel指数比较无统计学意义。结论早期肠内营养能够改善急性脑卒中伴Cushing溃疡的患者溃疡状况,能够改善急性卒中神经功能的近期预后,但是,Barthel指数无统计学意义。
出处 《中国医药指南》 2012年第17期271-272,共2页 Guide of China Medicine
  • 相关文献

参考文献8

二级参考文献48

  • 1顾美琴,施君伟,朱爱萍.应激性溃疡发病机制及临床防治[J].现代康复,1998,2(4):324-326. 被引量:2
  • 2王锡霞.应激性溃疡出血22例临床分析[J].河北医药,1994,16(6):390-390. 被引量:2
  • 3各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33020
  • 4崔巍,马力,闻颖,刘沛.暴发性肝衰竭时肠上皮细胞间紧密连接蛋白occludin表达下降[J].世界华人消化杂志,2006,14(31):3008-3012. 被引量:14
  • 5吴在德.外科学[M].北京:人民卫生出版社,2001.157.
  • 6Kansagra K,Stoll B,Rognerud C,et al.Total parenteral nutrition adversely affects gut barrier function in neonatal piglets.Am J Physiol Gastrointest Liver Physiol,2003;285(6):G1162-1170.
  • 7Steiger E.A technique for long term intravenous feeding in unrestrained rats.Arch Surg,1972;104(3):330-334.
  • 8Berkes J,Viswanathan VK,Sarkovic SD,et al.Intestinal epithelial responses to enteric pathogens:effect on the tight junction barrier,ion transport,and inflammation.Gut,2003;52(3):439-451.
  • 9Mazzon E,Sturniolo GC,Puzzolo D,et al.Effect of stress on the paracellular barrier in the rat ileum.Gut,2002;51(4):507-513.
  • 10Chen YH,Lu Q,Goodenough DA,et al.Nonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine kidney epithelial cells.Mol Biol Cell,2002;13(4):1227-1237.

共引文献33396

同被引文献32

  • 1郁正亚.围手术期抗凝药物的使用[J].中华临床医师杂志(电子版),2011,5(16):4778-4783. 被引量:12
  • 2陈少川,吴学良,许琳婷.奥美拉唑钠联合云南白药治疗应激性溃疡出血疗效观察[J].求医问药(下半月),2013(2):454-454. 被引量:5
  • 3Davis J P, Wong A A, Schuster P J, et al. Impact of pre- morbid under nutrition on outcome in stroke patients [ J ]. Stroke, 2004, 35(8): 1930.
  • 4Yco S H, Kim J S, Kwon S U, et al. Under nutrition as aphetic -tor of poor clinical outcomes in acute ischemic stroke patients[J]. Arch Neurol,2008, 65(1) : 39.
  • 5Martino R, Foley N, Bhopal S, et al. Dysphasia after stroke: incidence, diagnosis, and pulmonary complications [J ]. Stroke, 2005, 36: 2756.
  • 6朱天忠,卢长云.云南白药的药理及临床研究进展[J].中西医结合杂志.1987(06)
  • 7Manuel Bustamante,Neil Stollman.The Efficacy of Proton-pump Inhibitors in Acute Ulcer Bleeding: A Qualitative Review[J].Journal of Clinical Gastroenterology.2000(1)
  • 8Kuan AS, Chen SC, Yeh CM, et al. Risk of Ischemic Stroke in Patients With Gastric Cancer: A Nationwide Population-Based Co- hort Study [ J~. Medicine (Baltimore) ,2015,94 ( 37 ) : e1336.
  • 9Mashour GA, Shanks AM, Kheterpal S. Perioperative stroke and associated mortality after noncardiac, nonneurologic surgery [ J ]. Anesthesiology ,2011,114 (6) : 1289-1296.
  • 10Aoki J, Uchino K. Treatment of risk factors to prevent stroke[ J] Neurotherapeutics, 2011,8 ( 3 ) : 463-474.

引证文献4

二级引证文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部