病灶切除术联合术后药物治疗子宫腺肌瘤临床效果分析

Clinical effect analysis on excision surgery combined with postoperative medication adenomyosis

目的探讨子宫腺肌瘤病灶切除术联合不同药物治疗的治疗效果，为该病的治疗提供临床依据。方法将所有患者按照治疗方法随机分为A、B、C三组，分别为手术加达菲林组、手术加口服避孕药组和单纯手术组，观察比较三组手术前后的VAS评分、月经状况、痛经程度及并发症的发生状况。结果A、B、C三组治疗前的VAS评分分别为（5．29±3．61）、（5．32±3．52）、（5．31±3．38），差异无显著性（P〉0．05）治疗后三组VAS评分均显著降低，分别为（0．92±0．73）、（2．01±1．03）、（1．90±1．18），A组的得分显著低于其他两组，差异有显著性（P〈0．05）。A组患者痛经缓解率为100％，三组间的差异有显著性（P〈0．05）。三组患者均未出现严重并发症。结论病灶切除术联合达菲林治疗子宫腺肌瘤能够有效改善痛经、月经过多等症状，特别对于有生育要求的患者，是一种安全有效的方法。

Objective To investigate the curative effects of uterine adenomyosis lesion resection combined with different drug treatment, providing clinical basis for the treatment. Methods All patients were randomly divided into group A, B and C according to different treatments, surgery plus Diphereline group, surgery plus oral contraceptive group and surgery alone group. VAS scores, dysmenorrhea, and complications of the three groups were observed and compared. Results The pre-treatment VAS scores of the groups had no significant difference （P〉0.05）. The VAS scores of three groups after treatment were significantly reduced, and the surgery plus Diphereline group scored significantly lower than the other two groups, the difference was statistically significant （P〈0.05）. All patients＇ dysmenorrhea in surgery plus Diphereline group relieved, and there was a statistically significant difference among the three groups （P〈0.05）. Surgery plus Diphereline group was superior to the other two groups. No serious complications happened in three groups. Conclusion Surgery plus Diphereline treatment to uterine adenomyoma patients can effectively improve dysmenorrhea, menorrhagia and other symptoms, which is a safe and effective method for fertility patients.