肺炎性肌纤维母细胞瘤误诊中央型肺癌1例分析并文献复习

Pulmonary inflammatory myofibmblastic tumor misdiagnosed as central lung cancer:a case report and literature review

目的探讨肺炎性肌纤维母细胞瘤的临床诊断和治疗。方法对1例肺炎性肌纤维母细胞瘤的治疗及预后进行回顾性分析,并复习相关文献。结果报告1例肺炎性肌纤维母细胞瘤,男性,54岁,表现为咳嗽伴右胸痛,初步诊断右肺中央型肺癌,行右全肺切除治疗,术后病理及免疫组化结果证实为肺炎性肌纤维母细胞瘤,术后恢复顺利,康复出院,随访1a,无肿瘤复发及转移。结论肺炎性肌纤维母细胞瘤的诊断需综合术前临床表现、胸部影像学检查,术中所见,术后常规病理学检查、免疫组化结果。手术切除惟一有效的治疗措施。

Objective To evaluate the diagnosis and treatment of pulmonary inflammatory myofibmblastic tumor （IMT）. Methods One patienfs clinical database for the therapy and prognosis who suffered from pulmonary IMT was retrospectively analyzed,and the relative literature was reviewed. Results We reported a patient of 54-year-old man diagnosed as pulmonary IMT,who presented with the symptoms of cough and right chest pain for one month. The preliminary diagnosis was right central lung cancer and the patient received a right pneumonectomy. Pathological examination and immunohistochemical staining demonstrated the diagnosis pulmonary myofibroblastoma. The patient had an eventful recovery and was discharged,with no tumor recurrence or metastasis one year postoperatively. Con- clusion The diagnosis of pulmonary IM^T dependends on preoperative clinical symptoms, thoracic imaging, perioper- ative findings,postoperative pathological examination and immunohistochemical staining of the tumor. Complete re- section of the tumor is the only way achieving full rehabilation.