无症状慢性非细菌性前列腺炎的免疫因素的研究

目的通过测定无症状慢性非细菌性前列腺炎的血清白介素水平,探讨无症状慢性非细菌性前列腺炎和免疫因素的关系。方法采用引入生物素-亲合素系统的双抗体夹心ELISA法测定IL-2、IL-4、IL-6和IL-8。结果无症状慢性非细菌性前列腺炎(NIH分类Ⅳ型组)和有症状性慢性非细菌性前列腺炎(NIH分类Ⅲ型组)血清IL-2、IL-4、IL-6、IL-8均明显高于对照组(P<0.01),Ⅳ型组和Ⅲ型组比较无明显差异(P>0.05)。结论无症状慢性非细菌性前列腺炎的炎性反应与有症状的前列腺炎一致,也可能造成对机体的损伤,故对于严重的Ⅳ型前列腺炎患者需要一定的干预。

Objective This study aimed to discover the relatiomhip between the immune factors and asymptomafic Chronic Non-Bacterial Prostatitis by measuring the level of serum interleukin. Methods Double Antibody Sandwich Biotin-streptavidin ELISA Assay was employed to examine sera IL-2, IL-4, IL-6 and IL-8. Results Samples from both asymptomatic chronic non-bacterial prostatitis group （category NIH, type IV） and asymptomatic chronic bacterial prostatitis group （category NIH, type III） and group showed significant differences in the sera counts between the two experimental （P〈0.01）. However, the differences in the sera counts between the two experimental groups, type IV and type llI, were insignificant （P〉0.05）. Conclusion The findings suggested that, like symptomatic chronic non-bacterial prostatitis, asymptomatic chronic non-bacterial prostatitis may also cause damage to patients. Therefore, medical attentions should be paid to patients with severe cases of type IV prostatitis.