腰椎间盘突出症与腰椎骨密度的相关性研究

Correlation between lumbar disc herniation and bone mineral density of the lumbar vertebra

目的研究腰椎间盘突出症(lambar disc herniation,LDH)与骨质疏松(osteoporosis,OP)的相关性,探讨腰椎间盘突出症对骨密度的影响。方法选取腰椎间盘突出症组患者82例,对照组健康体检人群41例,利用定量CT(quantitative computed tomography,QCT)测定其骨密度(bone mineraldensity,BMD),分析比较两组的骨密度值。并对腰椎间盘突出症组患者病程:≤1年与>1年,腹肌肌力≤3级与≥4级骨密度值变化进行比较分析。结果腰椎间盘突出症组患者的骨密度值较对照组低,骨量减少者在腰椎间盘突出症组中的构成比较对照组高,但差异均无统计学意义(P>0.05)。其病程、腹肌肌力对腰椎间盘突出症组患者骨密度值变化的影响无统计学差异(P>0.05)。结论腰椎间盘突出症对骨密度有一定的影响,但两者的关系不显著,腰椎间盘突出症并非骨质疏松的独立影响因素。

Objective To investigate the correlation between lumbar disc herniation （LDH） and osteoporosis （OP） and to explore the effect of lumbar disc herniation on bone mineral density （BMD）. Methods Eightytwo LDH patients and 41 healthy people were chosen. BMD was detected using quantitative computed tomography （QCT） and analyzed. The BMD variation of LDH patients between less than 1 year and more than 1 year with the disease was compared. BMD between LDH patients with abdominal muscle tension less than 3 and LDH patients with abdominal muscle tension more than 4 was compared. Results BMD in LDH patients was lower than that in healthy people and the proportion of osteopenia patients in LDH group was more than that of the control group. However, the differences were not significant （P 〉 0. 05）. The effects of disease course and abdominal muscle tension on BMD of LDH patients had no statistically significant difference. Conclusion LDH has some impact on BMD, but the correlation is not significant. LDH is not an independent factor for osteoporosis.