急性脑卒中患者与医院获得性肺感染的临床研究

Clinical Study on Hospital Acquired Pneumonia in Patients with Acute Stroke

目的分析脑卒中患者急性期病情与医院获得性肺感染(HAP)的相关性。方法连续选择近期住院的急性脑卒中合并117例,入选对象接受了"脑卒中急性期病情和临床表现观察表"调查。结果 117例急性脑卒中患者中,住院期间发生HAP者55例(47.01%),未发生HAP者62例(52.99%)。发生HAP组的CT中线移位例数、急性期合并症数目、平均住院天数和OHS评分均显著高于未发生HAP组,而前者平均MMSE评分、平均MODS评分、平均NIHSS评分和MBI评分也明显低于未发生HAP组(P均<0.01或0.05)。结论急性期病情重、临床表现差的脑卒中患者较容易发生HAP。

Objective To analysis the relation between acute phase of illness in patients with stroke and hospital acquired pneumonia （HAP）. Methods 117 patients with acute stroke recent hospitalization were selected to accept the observation form about acute phase of illness and clinical manifestation of stroke. Results In 117 patients with acute stroke, HAP occurred in 55 inpatients （47.01%）, 62 （52.99%） inpatients without HAP. In stroke inpatients with HAP, CT midline displacement, complication, mean hospitalization time, OHS score were obviously higher than those in stroke inpatients without HAP, but the mean scores of MMSE, MODS, NIHSS and MBI were obviously lower than those in stroke inpatients without HAP（P〈0.05 or 0.01）. Conclusion Severe illness in acute phase and poor manifestation in patients with stroke is easy to occur HAP.