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B型尿钠肽在急性冠脉综合征中的变化特点 被引量:1

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摘要 目的:观察急性冠脉综合征(ACS),即不稳定心绞痛(UA)、ST段抬高型或非ST段抬高型心梗(STEMI或NSTEMI)中B型尿钠肽(BNP)的变化特点。方法:研究对象为150例ACS患者及100例健康体检者,并参照ACS不同类别和是否急诊经皮冠状动脉介入(PCI)治疗进行分组,采用Student-t检验和ANOVA分析对比各组间BNP水平和心功能相关指标的差异。结果:ACS后2~7 d,患者BNP水平显著升高(P<0.01),是对照组的19倍;与首发ACS组对比,再发组BNP水平和LnBNP均显著升高(P<0.01);与未急诊PCI组对比,急诊PCI组虽然血肌酸激酶同工酶(CK-MB)、肌钙蛋白T(TnT)显著升高(P<0.05),但BNP水平显著降低(P<0.05)。结论:ACS后,血BNP水平显著升高,以再发ACS、未行急诊PCI治疗者更高。
作者 钱正瑶
出处 《包头医学院学报》 CAS 2012年第3期53-55,共3页 Journal of Baotou Medical College
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