超声引导下不同布针策略在肝癌射频消融治疗中的临床价值

The clinical significance of different sequence in radiofrequency ablation of liver caner guided by ultrasound

目的探讨超声引导下不同布针策略在肝癌射频消融治疗中的临床价值。方法拟对62例肝癌（经临床确诊或经病理确诊）患者62个病灶行超声引导下经皮射频消融治疗，将患者随机分为2组：A组从肿瘤中央开始布针，顺序向周边延伸；B组从肿瘤周边开始布针，顺序向中央延伸。治疗后3个月复查彩超或增强CT，评价病灶消融效果。结果两种布针方法消融治疗有效部分差异无统计学意义（P〉0．05），但是A方法消融效果好的部分多于B方法，有更多的病灶完全毁损，两者差异有统计学意义（P〈0．05）。结论两种不同布针方法RFA治疗肝癌均有效，但从肿瘤中央开始布针，顺序向周边延伸的方法优于从肿瘤周边开始布针，顺序向中央延伸的方法。

Objective To evaluate the clinical significance of different sequences in Radiofrequency ablation of Liver caner guided by ultrasound. Methods Ultrasound guided percutaneous RFA was performed randomly by the same doctor in 62 tumors（ clinically definited or pathology definited} of 62 patients with two defferent sequences. Group A was from center parts of a tumor to peripheries, Group B was opposite. The ablation effectiveness was evaluated by enhanced CT or ultrasound three months later. Results There were not significant differences of improved patients between Group A and Group B （P〉0.05）, but sequence A and sequence B were statistically significant in better parts（the quantity： Group A 〉 Group B）of improved patients. Conclusions The two strategies of RFA for treating bepatocellular carcinoma are utility, but A is better.