云克治疗绝经后2型糖尿病合并骨质疏松症的疗效研究

Efficacy of 99Tc methylene diphosphate in treating type 2 diabetic patients combined with postmenopausal osteoporosis

目的探讨云克（锝亚甲基二磷酸盐针剂）治疗绝经后2型糖尿病患者合并骨质疏松症疗效观察。方法诊断明确的绝经后2型糖尿病合并骨质疏松症患者59例随机分为治疗组和对照组，治疗组综合治疗基础上应用锝亚甲基二膦酸盐针剂联合口服钙尔奇D片、骨化三醇胶丸，对照组口服钙尔奇D片、骨化三醇胶丸。结果治疗组6个月后骨密度不同程度增加，临床症状改善，总有效率93．5％，差异有统计学意义（P〈0．05）。结论云克治疗绝经后2型糖尿病合并骨质疏松症安全有效。

Objective To observe the effect of 99Tc methylene dipbosphate （99Tc MDP, Yunke） combined with calcium tablet and calcitriol in treating type 2 diabetic patients combined with postmenopausal osteoporosis. Methods 59 type 2 diabetic patients combined with postmenopausal osteoporosis patients were randomly divided into the t reatment group （n= 32） and control group（n= 28}. The treatment group was treated with vein injecting Yunke combined with calcium tablet and calcitrioln. The control group was treated only with calcium tablet and calcitriol. The therapy went on for 6 months. Results After 6 months, the treatment group was statistically superior to control group in each part of mean BMD （P〈0.05）, and amelioration rate was 93.5 %. The BMD raise respectively compared with pre-therapy period in treatment group. Conclusions It is safe and effective for 99Tc methylene diphosphate combined with calcium tablet and calcitriol in treating type 2 diabetic patients with postmenopausal osteoporosis.