缺血性脑卒中患者早期康复疗效的影响因素分析

Analysis of risk factors of early recovery in patients with ischemic stroke

目的 探讨影响缺血性脑卒中（IS）患者早期康复疗效的相关危险因素。方法 共纳入168例IS患者,常规治疗的同时,均给予早期康复治疗,并对早期康复治疗患者中成功康复与未成功康复患者以单因素分析筛选出有统计学意义的危险因素,再应用多因素非条件Logistic回归分析早期康复疗效的独立危险因素。结果 单因素分析显示：年龄（≥60岁）、高血压病史、冠心病病史、糖尿病史、吸烟史、焦虑及抑郁与成功康复呈负相关,生活规律、受教育程度（≥12年）及脑力劳动者与成功康复呈正相关;多因素分析显示：受教育程度（≥12年）（OR=0.12,95% CI 0.03~0.75）、脑力劳动者（OR=0.45,95% CI 0.37~0.47）是成功康复的保护因素（P〈0.05）;而年龄（≥60岁）（OR=2.12,95% CI 1.21~3.21）、焦虑（OR=2.64,95% CI 1.82~6.11）及抑郁（OR=1.45,95% CI 1.13~1.96）是成功康复的独立危险因素（P〈0.05）。结论 年龄（≥60岁）、焦虑及抑郁是成功康复的独立危险因素,对早期康复治疗IS患者的危险因素应进行必要的干预。

Objective To investigate the risk factors of early recovery in patients with ischemic stroke（IS）.Methods 168 patients with IS received the conventional treatment and early rehabilitation were enrolled in the study.Single factor analysis was used to analyze the risk factors of the IS in the early treatment of rehabilitation in patients with and without success recovery rehabilitation success,and then application （unconditional Logistic regression analysis factors early independent risk factors for healing.Results Single factor analysis shows that age quartile （60 years old）,history of hypertension,coronary heart disease, diabetes,history,history of smoking history,anxiety and depression and successful rehabilitation negatively,life,education degree by law quartile （12 years） and mental work positively correlated with successful recovery．Many factors analysis shows that education degree by quartile （12） （OR=0.12, 95% CI 0.03 to 0.75）,mental workers （OR=0.45,95% CI 0.37 to 0.47） is the success of the recovery protection factor （P〈0.05）,And age quartile （60） （OR=2.12, 95% CI 1.21 to 3.21）,anxiety （OR=2.64,95% CI 1.82 to 6.11） and depression （OR=1.45, 95% CI 1.13 to 1.96） is the success of the recovery independent risk factors （P〈 0.05）.Conclusion Age quartile （60）,anxiety and depression are IS successful independent risk factors for the recovery of the patients with early rehabilitation IS the risk factors should undertake the necessary intervention.